Statins, good or bad.

Looking for advise on hospitals, dentists and other health issues? Ask here.
yartims
udonmap.com
Posts: 758
Joined: July 23, 2018, 11:14 pm

Re: Statins, good or bad.

Post by yartims » July 25, 2018, 7:55 pm

i alternate between aspirin and clopidogrel ..hey all have their side effects but try to take as less tabs as possible..otherwise quality of life descends .i take the view that statins damage the liver as i know whats doing me good or bad


the only good Tory is a lavatory

yartims
udonmap.com
Posts: 758
Joined: July 23, 2018, 11:14 pm

Re: Statins, good or bad.

Post by yartims » August 1, 2018, 5:56 pm

https://www.telegraph.co.uk/news/health ... -good.html

Why I've ditched statins for good

As experts clash over proposals that millions more of us take statins to prevent heart disease and stroke, a vascular surgeon explains why he feels better without them
the only good Tory is a lavatory

yartims
udonmap.com
Posts: 758
Joined: July 23, 2018, 11:14 pm

Re: Statins, good or bad.

Post by yartims » August 25, 2018, 5:37 pm

There is a growing question mark over a commonly prescribed type of drug to lower cholestorol.

Some scientists and doctors believe statins are overused, but the latest round of debate in France goes even further.

Professors Bernard Debré and Philippe Even have published a guidebook for thousands of drugs – and they believe statins are useless.

Statin supporters

Since his heart attack, 44 year old Stéphane Ricois has regular appointments at a major hospital in Paris.

He has an unhealthy diet, he smokes and does not exercise, combining all the major risk factors. His specialist is particularly concerned about his high level of cholestorol.

“Before the doctor told me, I didn’t know I had high cholesterol. I’d never done the analysis before, because I was feeling fine.”

Now he takes Crestor, a drug in the statin family. Despite the controversy, many doctors still believe they prevent high cholesterol levels and cardio-vascular problems.

Senior cardiologist at Georges Pompidou Hospital, Nicolas Danchin said: “In coronary patients, that is people who have had a heart attack or angina, statins not only reduce the risk of having a recurrence, but quite simply they lower the risk of death or, more accurately, put the risk of death further away, and raise the life expectancy of these patients in a quite significant manner”.

Statins are among the most prescribed drugs in the world. In France they are used by at least 4-million people, costing the insurance companies 1.5-billion euros a year.

The French drug regulation agency ANSM believes they are an important weapon in a doctor’s arsenal.

Manager Joseph Emmerich said: “These drugs have been extremely well scrutinized for side effects and, anyway, there are not many drugs that can reduce mortality by 10% like statins.”

The alternative view

Not everyone though is such a fan. Renaud de Langlade heads several companies in the field of advanced electronics.

He took statins for ten years because his cholestorol readings were high.

It was a decade of painful side-effects, professional problems and a family crisis.

Now he has ditched the statins and he is back on top again.

“Mainly I felt fatigue. When I came home I was drained. I had no energy, nothing. And when I say I had no motivation I mean none whatsoever,” Langlade explained.

“In the morning when I was back in the office, I was not 100% with the clients. But when I stopped the statins, even before I started exercise again, I felt much better, 10 times better, No more anxiety or stress, no more troubles and I could sleep. I returned to the normal workrate I had before. “

One leading cardiologist has changed his mind about statins.

Michel de Lorgeril from Grenoble University now believes they serve no purpose in lowering cholestorol to prevent cardiac problems. Indeed he even thinks they are dangerous.

“We’ll come to the inevitable conclusion in the end that these drugs are unnecessary and toxic, they must be removed from the market and the health service must stop paying for them,” Lorgeril said. “As professors Even and Debré have already said, if you really want to protect yourself from heart disease and stroke, you should turn to something other than anti-cholesterol drugs.”

There are already other ways of looking after your heart that are unanimously endorsed by medical world.

Exercise is one. Saying goodbye to tobacco and animal fat is another, and saying hello to a Mediterranean style diet, full of fresh veg.

http://www.euronews.com/2013/03/19/stat ... ing-debate
the only good Tory is a lavatory

yartims
udonmap.com
Posts: 758
Joined: July 23, 2018, 11:14 pm

Re: Statins, good or bad.

Post by yartims » August 25, 2018, 5:48 pm

5. A heart-failure drug offers hope

We thought we had reached our limits in our ability to effectively treat heart failure. But in clinical trials, a new drug called LCZ696 cut the risk of death and hospitalizations by 20 percent, compared with enalapril, our gold standard drug for the past 20 years. The Food and Drug Administration has put LCZ696 on fast-track status; it may be approved this year.
the only good Tory is a lavatory

yartims
udonmap.com
Posts: 758
Joined: July 23, 2018, 11:14 pm

Re: Statins, good or bad.

Post by yartims » August 25, 2018, 5:58 pm

Decorative image
Does high cholesterol run in your family? Why Familial Hypercholesterolaemia is called the ‘silent assassin’
Some 120,000 Britons are at risk of heart disease and stroke due to inherited high cholesterol – and many don’t even know it. Could you have Familial Hypercholesterolaemia?

Does high cholesterol run in your family?
Lisa Salmon
By Lisa Salmon
Last updated: 12 July 2015, 17:23 BST
Print this story

Has someone in your family had a heart attack or stroke at a very young age, or has a routine test shown your cholesterol levels are very high? If so, you could have Familial Hypercholesterolaemia (FH), one of the most common genetic conditions in the UK.

FH is known as the 'silent assassin' because although it can cause exceptionally high cholesterol levels leading to an increased risk of early heart disease, stroke and death, 85% of people with the condition remain undiagnosed and untreated.

It occurs in at least one in 500 people (120,000) in the UK who've inherited a faulty gene from one or both parents which leaves the body unable to process cholesterol properly. People with the condition may have cholesterol levels that are double or triple those of the general population.

Now a new campaign, Heart of the Family, is trying to raise awareness of FH and is urging people to get tested for it if they have a family history of early heart attack or stroke, or if they already know they have FH in the family.

The symptoms of FH

The two main indicators of FH are abnormally high levels of cholesterol, and a family history of high cholesterol or early heart disease, including heart attacks and stroke.

Most people don't show visible signs of FH, meaning the condition may not be diagnosed until cardiovascular problems become apparent. However, sometimes there are visible symptoms, especially when LDL-C (‘Bad’ cholesterol) is very high. These include:

• Swollen tendons on the back of the heel (xanthoma) and hand.
• Yellow deposits in the skin around the eyes (xanthelasmata).
• A white deposit of cholesterol in the shape of an arc around the coloured part of the eye (corneal arcus).

An FH diagnosis may be confirmed by a genetic test, but as every possible genetic variant isn't yet understood, the diagnosis can also be made on clinical grounds.

Once a diagnosis is confirmed, it's important that all family members including siblings, children, parents, grandparents and first cousins are tested for the condition.

What causes FH?

FH isn't caused by an unhealthy lifestyle, but from inheriting a defective gene from at least one parent. Each child has a 50% risk of inheriting FH if one of their parents has the faulty gene.

Someone with FH will have had high levels of cholesterol from birth – not just from middle-age, as is the case with many people without FH who have high cholesterol (common hypercholesterolaemia).

Bad cholestorol

The type of cholesterol that increases in FH is low-density lipoprotein cholesterol (LDL-C or ‘bad’ cholesterol), which can block or narrow blood vessels and increase the risk of heart disease and stroke.

In fact, 50% of men and 30% of women with FH will have developed heart disease by the time they're 50 and 60 years old respectively.

Treating FH

Although FH isn't curable, drugs and lifestyle measures can help reduce the build-up of the blood vessel-blocking fatty deposits produced by too much LDL-C.

To reduce the risk of FH causing serious or even fatal harm, people with the condition should:

• Stop smoking;
• Only drink alcohol in moderation;
• Maintain a healthy weight;
• Exercise regularly;
• Eat a healthy diet including five-a-day fruit and veg and other heart-healthy foods such as soya, wholegrains, and foods rich in unsaturated fats like nuts, oily fish and avocado;
• Take cholesterol-lowering medications.

What the experts say

Jules Payne, chief executive of the cholesterol charity Heart UK, stresses: “Early diagnosis and effective treatment reduces the risk of heart disease and can help ensure that people with FH have a normal life expectancy.”

And GP Dr Sarah Jarvis, past chair of the Heart UK healthcare committee, adds: “While siblings and children of someone with FH have a 50% risk of inheriting it themselves, it can also affect second and third generation relatives, so it's vital that family members are tested for FH as early as possible.

“FH is a silent assassin and too often goes undetected until it’s too late.”

For more information about FH, visit Heart of the Family.


Decorative image
Does high cholesterol run in your family? Why Familial Hypercholesterolaemia is called the ‘silent assassin’
Some 120,000 Britons are at risk of heart disease and stroke due to inherited high cholesterol – and many don’t even know it. Could you have Familial Hypercholesterolaemia?

Does high cholesterol run in your family?
Lisa Salmon
By Lisa Salmon
Last updated: 12 July 2015, 17:23 BST
Print this story

Has someone in your family had a heart attack or stroke at a very young age, or has a routine test shown your cholesterol levels are very high? If so, you could have Familial Hypercholesterolaemia (FH), one of the most common genetic conditions in the UK.

FH is known as the 'silent assassin' because although it can cause exceptionally high cholesterol levels leading to an increased risk of early heart disease, stroke and death, 85% of people with the condition remain undiagnosed and untreated.

It occurs in at least one in 500 people (120,000) in the UK who've inherited a faulty gene from one or both parents which leaves the body unable to process cholesterol properly. People with the condition may have cholesterol levels that are double or triple those of the general population.

Now a new campaign, Heart of the Family, is trying to raise awareness of FH and is urging people to get tested for it if they have a family history of early heart attack or stroke, or if they already know they have FH in the family.

The symptoms of FH

The two main indicators of FH are abnormally high levels of cholesterol, and a family history of high cholesterol or early heart disease, including heart attacks and stroke.

Most people don't show visible signs of FH, meaning the condition may not be diagnosed until cardiovascular problems become apparent. However, sometimes there are visible symptoms, especially when LDL-C (‘Bad’ cholesterol) is very high. These include:

• Swollen tendons on the back of the heel (xanthoma) and hand.
• Yellow deposits in the skin around the eyes (xanthelasmata).
• A white deposit of cholesterol in the shape of an arc around the coloured part of the eye (corneal arcus).

An FH diagnosis may be confirmed by a genetic test, but as every possible genetic variant isn't yet understood, the diagnosis can also be made on clinical grounds.

Once a diagnosis is confirmed, it's important that all family members including siblings, children, parents, grandparents and first cousins are tested for the condition.

What causes FH?

FH isn't caused by an unhealthy lifestyle, but from inheriting a defective gene from at least one parent. Each child has a 50% risk of inheriting FH if one of their parents has the faulty gene.

Someone with FH will have had high levels of cholesterol from birth – not just from middle-age, as is the case with many people without FH who have high cholesterol (common hypercholesterolaemia).

Bad cholestorol

The type of cholesterol that increases in FH is low-density lipoprotein cholesterol (LDL-C or ‘bad’ cholesterol), which can block or narrow blood vessels and increase the risk of heart disease and stroke.

In fact, 50% of men and 30% of women with FH will have developed heart disease by the time they're 50 and 60 years old respectively.

Treating FH

Although FH isn't curable, drugs and lifestyle measures can help reduce the build-up of the blood vessel-blocking fatty deposits produced by too much LDL-C.

To reduce the risk of FH causing serious or even fatal harm, people with the condition should:

• Stop smoking;
• Only drink alcohol in moderation;
• Maintain a healthy weight;
• Exercise regularly;
• Eat a healthy diet including five-a-day fruit and veg and other heart-healthy foods such as soya, wholegrains, and foods rich in unsaturated fats like nuts, oily fish and avocado;
• Take cholesterol-lowering medications.

What the experts say

Jules Payne, chief executive of the cholesterol charity Heart UK, stresses: “Early diagnosis and effective treatment reduces the risk of heart disease and can help ensure that people with FH have a normal life expectancy.”

And GP Dr Sarah Jarvis, past chair of the Heart UK healthcare committee, adds: “While siblings and children of someone with FH have a 50% risk of inheriting it themselves, it can also affect second and third generation relatives, so it's vital that family members are tested for FH as early as possible.

“FH is a silent assassin and too often goes undetected until it’s too late.”

For more information about FH, visit Heart of the Family.

Decorative image
Does high cholesterol run in your family? Why Familial Hypercholesterolaemia is called the ‘silent assassin’
Some 120,000 Britons are at risk of heart disease and stroke due to inherited high cholesterol – and many don’t even know it. Could you have Familial Hypercholesterolaemia?

Does high cholesterol run in your family?
Lisa Salmon
By Lisa Salmon
Last updated: 12 July 2015, 17:23 BST
Print this story

Has someone in your family had a heart attack or stroke at a very young age, or has a routine test shown your cholesterol levels are very high? If so, you could have Familial Hypercholesterolaemia (FH), one of the most common genetic conditions in the UK.

FH is known as the 'silent assassin' because although it can cause exceptionally high cholesterol levels leading to an increased risk of early heart disease, stroke and death, 85% of people with the condition remain undiagnosed and untreated.

It occurs in at least one in 500 people (120,000) in the UK who've inherited a faulty gene from one or both parents which leaves the body unable to process cholesterol properly. People with the condition may have cholesterol levels that are double or triple those of the general population.

Now a new campaign, Heart of the Family, is trying to raise awareness of FH and is urging people to get tested for it if they have a family history of early heart attack or stroke, or if they already know they have FH in the family.

The symptoms of FH

The two main indicators of FH are abnormally high levels of cholesterol, and a family history of high cholesterol or early heart disease, including heart attacks and stroke.

Most people don't show visible signs of FH, meaning the condition may not be diagnosed until cardiovascular problems become apparent. However, sometimes there are visible symptoms, especially when LDL-C (‘Bad’ cholesterol) is very high. These include:

• Swollen tendons on the back of the heel (xanthoma) and hand.
• Yellow deposits in the skin around the eyes (xanthelasmata).
• A white deposit of cholesterol in the shape of an arc around the coloured part of the eye (corneal arcus).

An FH diagnosis may be confirmed by a genetic test, but as every possible genetic variant isn't yet understood, the diagnosis can also be made on clinical grounds.

Once a diagnosis is confirmed, it's important that all family members including siblings, children, parents, grandparents and first cousins are tested for the condition.

What causes FH?

FH isn't caused by an unhealthy lifestyle, but from inheriting a defective gene from at least one parent. Each child has a 50% risk of inheriting FH if one of their parents has the faulty gene.

Someone with FH will have had high levels of cholesterol from birth – not just from middle-age, as is the case with many people without FH who have high cholesterol (common hypercholesterolaemia).

Bad cholestorol

The type of cholesterol that increases in FH is low-density lipoprotein cholesterol (LDL-C or ‘bad’ cholesterol), which can block or narrow blood vessels and increase the risk of heart disease and stroke.

In fact, 50% of men and 30% of women with FH will have developed heart disease by the time they're 50 and 60 years old respectively.

Treating FH

Although FH isn't curable, drugs and lifestyle measures can help reduce the build-up of the blood vessel-blocking fatty deposits produced by too much LDL-C.

To reduce the risk of FH causing serious or even fatal harm, people with the condition should:

• Stop smoking;
• Only drink alcohol in moderation;
• Maintain a healthy weight;
• Exercise regularly;
• Eat a healthy diet including five-a-day fruit and veg and other heart-healthy foods such as soya, wholegrains, and foods rich in unsaturated fats like nuts, oily fish and avocado;
• Take cholesterol-lowering medications.

What the experts say

Jules Payne, chief executive of the cholesterol charity Heart UK, stresses: “Early diagnosis and effective treatment reduces the risk of heart disease and can help ensure that people with FH have a normal life expectancy.”

And GP Dr Sarah Jarvis, past chair of the Heart UK healthcare committee, adds: “While siblings and children of someone with FH have a 50% risk of inheriting it themselves, it can also affect second and third generation relatives, so it's vital that family members are tested for FH as early as possible.

“FH is a silent assassin and too often goes undetected until it’s too late.”

For more information about FH, visit Heart of the Family.
the only good Tory is a lavatory

yartims
udonmap.com
Posts: 758
Joined: July 23, 2018, 11:14 pm

Re: Statins, good or bad.

Post by yartims » September 18, 2018, 5:34 pm

more bad feedback on statins this week

https://www.express.co.uk/life-style/he ... ar-disease

Statins use ‘of doubtful benefit’
THERE is no evidence that high levels of “bad” cholesterol cause heart disease and the widespread use of statins is “of doubtful benefit”, according to a study by 17 international physicians.
By Gillian Crawley
PUBLISHED: 02:54, Tue, Sep 18, 2018 | UPDATED: 03:04, Tue, Sep 18, 2018


https://www.thesun.co.uk/news/7280954/h ... -evidence/

DOCTORS have found there is no evidence of a link between high levels of bad cholesterol and heart disease, a study says.

And with this claim, a number of leading cardiologists say statins, taken by millions of Brits to tackle cholesterol, don't have any benefit.

Their findings, published in the Expert Review of Clinical Pharmacology, suggest the drugs won't treat heart disease, as they say high bad cholesterol levels don't necessarily lead to heart disease.

The 17 physicians from across the world appear to have dispelled the theory that there are links between having high LDL-C levels - known as bad cholesterol - and fatty deposits that clog arteries.

Experts have clashed for years as they argue both for and against statins and their effect.

But while they do agree that they are a lifesaver for people who have already had a heart attack, the study based on about 1.3million patients' data indicates it could be of no use as a preventative measure.
the only good Tory is a lavatory

User avatar
Faraday
udonmap.com
Posts: 492
Joined: December 4, 2015, 10:53 pm

Re: Statins, good or bad.

Post by Faraday » September 18, 2018, 6:07 pm

If anyone knows the title of these findings, I can d/l it so we can have a proper look at what is said exactly.

yartims
udonmap.com
Posts: 758
Joined: July 23, 2018, 11:14 pm

Re: Statins, good or bad.

Post by yartims » April 26, 2019, 4:44 pm

https://www.bbc.co.uk/news/health-47933345

Cholesterol-lowering "statin" drugs taken by millions of Britons may not work well enough in about half of those prescribed them, research suggests.

UK investigators looked at 165,000 patients on statins and found that for one in two, the drugs had too little effect on bad cholesterol - one of the big risk factors for heart disease.

They are not sure why statins appear to help some more than others.

Patients should not stop taking the drugs without seeing their doctor.

One possible explanation is patients not taking their prescribed drugs or doctors giving them at too low doses, experts suggest.

Cardiovascular disease kills about 150,000 people in the UK each year.
the only good Tory is a lavatory

User avatar
AlexO
udonmap.com
Posts: 532
Joined: June 8, 2015, 11:45 am
Location: Nong Lat Udon

Re: Statins, good or bad.

Post by AlexO » April 26, 2019, 7:21 pm

UK Gov love this, no more paltry pension payouts.

yartims
udonmap.com
Posts: 758
Joined: July 23, 2018, 11:14 pm

Re: Statins, good or bad.

Post by yartims » July 31, 2019, 8:44 pm

another jive assed report on statins as they dont mention all the other factors involved like smoking drinking diet exercise that effects heart attacks on over 75s whether they take statins or not

https://www.independent.co.uk/news/heal ... 28381.html
the only good Tory is a lavatory

yartims
udonmap.com
Posts: 758
Joined: July 23, 2018, 11:14 pm

Re: Statins, good or bad.

Post by yartims » July 31, 2019, 9:07 pm

https://www.irishnews.com/lifestyle/201 ... s-1665848/

THESE drugs are an alternative to statins to treat high cholesterol and reduce the risk of heart disease, heart attack and stroke.

They work by inactivating a protein in the liver called proprotein convertase subtilisin kexin 9 (PCSK9) to reduce ‘bad' LDL cholesterol levels in the blood. Rather than daily tablets as with statins, they are injected once every two to four weeks.

Studies show evolocumab and alirocumab lower cholesterol levels in the blood by more than half. They also don't cause the side-effects associated with statins, such as muscle and joint pain – although long-term studies are needed as they reduce cholesterol to much lower levels than statins. The medicines were approved in 2016 but they are expensive, costing an estimated £4,000 per patient per year, compared with £12 a year for some statins. As a result, their use is often restricted to patients most at risk, such as those with familial hypercholesterolemia, a genetic condition that causes dangerously high cholesterol levels.

‘Both drugs have been shown to improve outcomes in patients with cardiovascular disease,' says Dr Andrew Chapman, a clinical lecturer in cardiology at the University of Edinburgh.

‘For example, in a large trial of evolocumab, “bad” cholesterol levels fell by 59 per cent, and future cardiovascular events [such as heart attack] were reduced by 15 per cent.

‘Although expensive, if these drugs reduce future risk and therefore use of other resources within the NHS, this may be justified.'
the only good Tory is a lavatory

Post Reply

Return to “Health & Beauty”